Barca moved eight points clear at the top of La Liga after a 3-0 win at home to Sevilla, coupled with a 1-0 defeat for Real Madrid in Mallorca.
Barca controlled most of their game against Sevilla but were unable to score after a series of excellent saves from Sevilla keeper Bono, reports Xinhua news agency.
Jordi Alba broke the deadlock in the 58th minute when the full-back finished off a long move that involved 17 passes.
Gavi doubled Barca's lead in the 70th minute, with a simple tap-in at the far post after an excellent pass from Raphinha and Rahpinha got a deserved goal with 10 minutes to go after being set up by Alba, who had broken the Sevilla offside trap.
Real Madrid lost 1-0 away to Mallorca, who scored in the first half when Vedat Muriqi's header was deflected over Andriy Lunin by Nacho Fernandez.
Lunin was a late replacement for Thibaut Courtois, who pulled up in warm-up after appearing to injure a groin muscle.
Madrid had most of the ball and most of the chances against an exceptionally solid rival and their best chance came on the hour when Marco Asensio saw his penalty saved by Predrag Rajkovic.
Cyle Larin's second goal in two games for Valladolid was enough to give his side consecutive wins and condemn third-place Real Sociedad to their first league defeat since October 30 last year.
The side from San Sebastian didn't have a good day in front of goal, and Larin punished them when he took advantage of Valladolid's only chance in the second half.
Atletico Madrid dropped two points in their home game against struggling Getafe, despite Angel Correa's slightly surreal opener.
The striker put the ball in the Getafe net in the 60th minute, only for the goal to be ruled out for offside. While the VAR was revising the play, he was substituted, which meant he was sitting in the dugout when the VAR gave the goal as legal.